		Technical Data
S5379-96	Spectrin, alpha (Spectrin alpha Chain, Spectrin alpha Chain Brain, Spectrin Non-erythroid alpha Chain, Alpha Fodrin, Alpha II Spectrin, FLJ44613, Fodrin alpha Chain, Non-erythrocytic Spectrin alpha, Spectrin alpha Non-erythrocytic 1, SPTAN1, SPTA2)

Description:
SPTAN1/Alpha II-spectrin is one of two polypeptide chains (alpha and beta) that are part of the fodrin tetramer. Fodrin functions to link actin filaments to the plasma membrane and is a major neuronal cytoskeletal protein. Fodrin has been linked to neurogenerative and autoimmune diseases. Alternate names for SPTAN1/Alpha II-spectrin include alpha-fodrin, spectrin alpha chain brain, spectrin non-erythroid alpha chain, fodrin alpha chain, SPTA2, and FLJ44613.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilutions:
Western Blot: 1:2000-1:10,000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ul		-20°C	Blue Ice	Human	Rabbit

Concentration:

~1mg/ml

Immunogen:

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7.5, 0.09% sodium azide

Specificity:

Recognizes human spectrin, alpha. Species Crossreactivity: mouse. The epitope maps to a region between residues 1000 and 1050 of human spectrin, alpha. (NP_003118.1)

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.