Technical Data
S5380-14
Spectrin Beta 3 (Beta III Spectrin, KIAA0302, Spectrin beta Chain Brain 2, Spectrin beta Non-erythrocytic 2, Spectrin Non-erythroid beta Chain 2, SPTBN2, Spinocerebellar Ataxia 5, SCA5, SCA 5)
Description:
Mutations in spectrins are a previously unknown cause of ataxia and neurodegenerative disease that affect membrane proteins involved in glutamate signaling. Spectrin-beta IIIs have been recognized as ataxia disease genes and their mutations cause spinocerebellar ataxia type 5 (SCA5).

Applications:
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanRabbit
Concentration:
~1
Immunogen:
The epitope recognized by this antibody maps to a C-terminal region between residue 2300 and 2390 of human spectrin, beta, non-erythrocytic 2 (spinocerebellar ataxia 5 ) using the numbering given in entry NP_008877.1. Homology: 100% with human, mouse, and
Purity:
Purified by immunoaffinity chromatography.
Form
Tris-citrate/phosphate buffer, pH 7 to 8
Specificity:
Species Crossreactivity: This antibody reacts with human. Other species have not been tested.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.