Technical Data
S7975-51D
Stromal Cell Derived Factor 1 alpha, Recombinant, Mouse (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1)
10ug
Growth Factors, Cytokines Storage: -20°CShipping: Blue Ice
SDF-1 alpha, otherwise known as CXCL12a, is a stromal cell derived CXC chemokine which, together with SDF-1 beta, arises from alternative splicing of the SDF-1 gene, and acts as a chemoattractant for T and B lymphocytes, monocytes and migratory neurons. SDF-1 binds with high-affinity to the G protein–coupled receptor CXCR4 (fusin), and acts as an inhibitor of the CXCR4-mediated entry of HIV-1 virus into target T-cells.

Source:
E. coli

Applications:
Suitable for use in Functional Assays. Other applications not tested.

Biological Activity:
Determined by its ability to chemoattract human peripheral blood monocytes, using a concentration of 50-100ng/ml.

Endotoxin: 1EU/ug

Molecular Weight: 7.9kD (68 amino acid residue homodimer)

Storage and Stability:
Lyophilized powder may be Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source: E. coli
Purity: 98% (SDS PAGE and HPLC).
Concentration: ~0.1mg/ml
Form: Supplied as a lyophilized powder. No stabilizing proteins added. No preservative added. Reconstitute in 100ul distilled water.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.