Technical Data
S7975-64
Stromal Cell Derived Factor 1beta, aa1-72, Recombinant, Mouse (SDF1b, CXCL12b, Pre-B Cell Growth-stimulating Factor, PBSF, hIRH, Chemokine (C-X-C Motif) Ligand 12b, TPAR1, SCYB12, TLSF-b)
2ug
10ug
10ug
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Technical Data |
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S7975-64 |
Stromal Cell Derived Factor 1beta, aa1-72, Recombinant, Mouse (SDF1b, CXCL12b, Pre-B Cell Growth-stimulating Factor, PBSF, hIRH, Chemokine (C-X-C Motif) Ligand 12b, TPAR1, SCYB12, TLSF-b) |
2ug 10ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: RT |
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Chemokine SDF-1 is highly conserved among species and belongs to a large family of small, structurally related cytokines. It is a chemoattractant for T lymphocytes, monocytes, and hemopoietic stem cells and is constitutively expressed in bone-marrow-derived stromal cells. Recent reports indicate that SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. SDF-1a and SDF-1b, are generated by alternative RNA splicing of transcripts encoded by a single gene. SDF-1a differs from SDF-1b by four C-terminal amino acid residues absent in SDF-1a. As yet, no functional differences have been reported. Stromal Cell-Derived Factor-1beta (SDF1b) is a recently discovered protein belonging to the a-chemokine (C-X-C) family of cytokines. Murine SDF1b is an 8.5kD protein containing 72 amino acid residues. Source: E. coli Form: Lyophilized protein without additives. Stability: Lyophilized SDF1b, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted human SDF1b should be stored in working aliquots at -20°C. Purity: 98% by SDS-PAGE and HPLC analyses. Endotoxin: 0.1ng/ug Reconstitution: Lyophilized SDF1b is soluble in water and most aqueous buffers. The lyophilized protein can be reconstituted in water to a concentration of 0.1-1mg/ml. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 50-100ng/ml Concentration Range for most in vitro applications: 0.1-1mg/ml AA Sequence: KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM Country of Origin: USA Molecular Weight: 8.5kD |
Source: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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