Technical Data
S7975-65A
Stromal cell-derived factor 1b, 22-93aa, Recombinant Human (SDF1b, CXCL12b, Pre-B Cell Growth-stimulating Factor, PBSF, hIRH, Chemokine (C-X-C Motif) Ligand 12b, TPAR1, SCYB12, TLSF-b)
50ug
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Technical Data |
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S7975-65A |
Stromal cell-derived factor 1b, 22-93aa, Recombinant Human (SDF1b, CXCL12b, Pre-B Cell Growth-stimulating Factor, PBSF, hIRH, Chemokine (C-X-C Motif) Ligand 12b, TPAR1, SCYB12, TLSF-b) |
50ug |
| Growth Factors, Cytokines | Storage: -70°CShipping: Dry Ice |
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SDF-1 is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). SDF-1 is strongly chemotactic for lymphocytes and works by its receptor CXCR4. The SDF-1+CXCR4 complex plays a significant role in the creation of metastases of neoplasms and as a response to cytostatic treatment. Identification of this complex may be a useful prognostic factor in the therapy of many types of carcinoma. Source: Recombinant human SDF-1, fused to His-tag at N-terminus, was expressed in E.coli. Sequence of amino acids: MGSSHHHHHH SSGLVPRGSH MKPVSLSYRC PCRFFESHVA RANVKHLKIL NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKR FKM Endotoxin Level: 1EU/ug Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at 20 or 70°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Molecular Weight: 10.8kD |
Source: His-tagged, Recombinant, E. coli Purity: 90% (SDS-PAGE) Concentration: ~0.5mg/ml Form: Supplied as liquid in 20mM Tris-HCl, pH8.0, 10% glycerol. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Arya M., et al. (2007). Tumour Biol. 28(3):123-31, 2. Kucia M., et al. (2005). Stem Cells. 23(7):879-94.
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