Technical Data
S7975-65A
Stromal cell-derived factor 1b, 22-93aa, Recombinant Human (SDF1b, CXCL12b, Pre-B Cell Growth-stimulating Factor, PBSF, hIRH, Chemokine (C-X-C Motif) Ligand 12b, TPAR1, SCYB12, TLSF-b)
50ug
Growth Factors, Cytokines Storage: -70CShipping: Dry Ice
SDF-1 is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). SDF-1 is strongly chemotactic for lymphocytes and works by its receptor CXCR4. The SDF-1+CXCR4 complex plays a significant role in the creation of metastases of neoplasms and as a response to cytostatic treatment. Identification of this complex may be a useful prognostic factor in the therapy of many types of carcinoma.

Source:
Recombinant human SDF-1, fused to His-tag at N-terminus, was expressed in E.coli.

Sequence of amino acids:
MGSSHHHHHH SSGLVPRGSH MKPVSLSYRC PCRFFESHVA RANVKHLKIL NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKR FKM

Endotoxin Level: 1EU/ug

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at 20 or 70C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight:
10.8kD
Source: His-tagged, Recombinant, E. coli
Purity: 90% (SDS-PAGE)
Concentration: ~0.5mg/ml
Form: Supplied as liquid in 20mM Tris-HCl, pH8.0, 10% glycerol.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Arya M., et al. (2007). Tumour Biol. 28(3):123-31, 2. Kucia M., et al. (2005). Stem Cells. 23(7):879-94.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.