Technical Data
S7981-01H
SMC2, CT (SMC Protein 2, Structural Maintenance Of Chromosomes Protein 2, Chromosome-associated Protein E, hCAP-E, XCAP-E Homolog, SMC-2, CAPE, SMC2L1, PRO0324)
Description:
SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the C-terminal region of human SMC2 (KLH).
Purity:
Purified by ammonium sulfate precipitation.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human SMC2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Schmiesing,J.A., Proc. Natl. Acad. Sci. USA 95(22), 12906-12911 (1998). 2. Ham,M.F., Cancer Sci. 98 (7), 1041-1047 (2007).