Technical Data
S8000
Substance P (NK, Neurokinin)
Description:
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C or colder. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2a8.F.264Purified
SizeStorageShippingSourceHost
500ul-20CBlue IceRat
Concentration:
Immunogen:
Substance-P (BSA coupled)
Purity:
Purified supernatant
Form
Lyophilized powder
Specificity:
Recognizes (~5%) Eledoisin. No crossreactivity with Leu- or Met-enkephalin, somatostatin or beta-endorphin.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.