Technical Data
S8000-01A
Substance P (NK, Neurokinin)
Description:
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:10,000
Immunohistochemistry (human): 1:1000
Immunohistochemistry (rat): 1:2000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG19L669Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to human Substance P (RPRPQQFFGLM).
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a lyophilized powder from 0.1M glycine PBS, pH 7.4. No preservative added. Reconstitute in 100ul sterile ddH2O.
Specificity:
Recognizes human Substance P. No cross reactivity against Neurokinin A, Neurokinin B or Kassinin. Species Crossreactivity: rat
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.