Technical Data
S8000-09
Substance P (NK, Neurokinin)
Description:
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Application(s): Suitable for use in immunoperoxidase and Immunofluorescence.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceChickenRabbit
Concentration:
Not determined
Immunogen:
Synthetic substance P bound to keyhole limpet hemocyanin (KLH) with carbodiimide.
Purity:
Serum.
Form
Liquid antiserum. Contains 0.1% sodium azide.
Specificity:
Stains nerve fibers in the external median eminence of the chicken and opossum.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Nairn, R. C. Fluorescent protein tracing. Livingstone, Edinburgh, (1964). 2. Sternberger, L. A. Immunocytochemistry. Wiley, New York (1979). 3. Ho, R. H., et al. Brain Res., 189:565569 (1980). 4. Hokfelt, T., et al. Proc. Natl. Acad. Sci., 75:10131015 (1978). 5. Hokfelt, T., et al. Neuroscience, 3:17538 (1978). 6. Hokfelt, T., et al. Brain Res., 100:235252 (1975).