Technical Data
S8060-10P
SOD2 (Superoxide Dismutase [Mn], Mitochondrial [Precursor], SOD2)
Description:
SOD2 is a member of the iron/manganese superoxide dismutase family. It is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.

Applications:
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:4,000
Western Blot: 1:2,000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG1,k10i73Affinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanMouse
Concentration:
As reported
Immunogen:
Purified His-tagged SOD protein (fragment).
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human SOD2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Fabre,E.E., Am. J. Clin. Nutr. 87(5), 1504-1512 (2008). 2.Kaewpila,S., Cancer Res. 68(8), 2781-2788 (2008). 3.Flekac,M., (er) BMC Med. Genet. 9, 30 (2008).