		Technical Data
S8060-10P	SOD2 (Superoxide Dismutase [Mn], Mitochondrial [Precursor], SOD2)

Description:
SOD2 is a member of the iron/manganese superoxide dismutase family. It is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.

Applications:
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:4,000
Western Blot: 1:2,000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Mab	IgG1,k	10i73	Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Mouse

Concentration:

~0.25mg/ml

Immunogen:

Purified His-tagged SOD protein (fragment).

Purity:

Purified by Protein G affinity chromatography.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human SOD2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1.Fabre,E.E., Am. J. Clin. Nutr. 87(5), 1504-1512 (2008). 2.Kaewpila,S., Cancer Res. 68(8), 2781-2788 (2008). 3.Flekac,M., (er) BMC Med. Genet. 9, 30 (2008).