Technical Data
S8060-30
Superoxide Dismutase 1 (SOD1)
Description:
Mutations in the copper/zinc superoxide dismutase (SOD1) gene are associated with 15-20% of the familial forms of motoneuron disease. This 153 amino acid metalloenzyme is expressed in virtually all cells of all organisms above bacteria and is highly conserved across species, although some minor variations do occur. The incorporation of the mutated form of the SOD1 human gene into a transgenic mouse leads to the onset of the disease that closely resembles the human condition. These animals become weak at about 2-4 months of age and rapidly lose function, which results in death 4-6 weeks later.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1:200-1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
50ul-20°CBlue IceMouseRabbit
Concentration:
Not Determined
Immunogen:
Synthetic peptide corresponding to aa25-37 of mouse SOD1.
Purity:
Serum
Form
Supplied as a lyophilized powder. Contains no preservatives. Reconstitute with 50ul sterile ddH2O.
Specificity:
Recognizes mouse Superoxide Dismutase 1 (SOD1). Species Crossreactivity: rat. Does not react with human SOD1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Bartlett, et al., J. Neuroscience Methods 98: 63-67 (2000).