Technical Data
T1030-03B
Tau (Tau Protein, Microtubule-associated Protein, MAP)
Description:
Tau proteins are microtubuleassociated proteins (MAPs). Alternate splicing of tau mRNA and differential phosphorylation contribute to the heterogeneity of tau.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistolochemistry (Formalin/paraffin): 1:50-1:100 for 30 min at RT. No special pretreatment is required.

Positive Control:
Alzheimer’s disease brain tissue

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
250ul4°C (-20°C Glycerol)Blue IceHumanRabbit
Concentration:
Not Determined
Immunogen:
Recombinant protein encoding C-terminal part of human tau. Cellular Localization: Cytoplasmic. Epitope: C-terminal. MW of Antigen: 45-68kD
Purity:
Serum
Form
Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide, before the addition of glycerol to 40%.
Specificity:
Recognizes human tau. Stains the human neurofibrillary tangles, neuropil threads, and neuritic plaques associated with Alzheimer’s disease. It also stains astrocytes and ribosomes.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Brion JP.. Neurosciences 1990; 2:89-100. 2. Goedert M et al.. Proc Natl Acad Sci 1988; 85:4051-5. 3. Butner KA et al. J Cell Biol 1991; 115:717-30