Technical Data
T3300-01
TSPAN8 (Tetraspanin 8, CO-029, TM4SF3, Transmembrane 4 Superfamily Member 3, Tumor-Associated Antigen CO-029) (APC)
Description:
Tetraspanin-8 (TSPAN8), is a member of the transmembrane 4 superfamily. It is a cell surface 27-34kD protein with 4 transmembrane segments, and a large extracellular loop (LEL) domain from aa106-206. Both the N- and C-termini are intracellular. The protein is involved in cell motility, metastasis, cell proliferation and differentiation, and is over-expressed in different carcinomas, including hepatocellular carcinoma and colon cancer. Human Tetraspanin-8 shares 70aa sequence identity with both mouse and rat TSPAN8.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Hybridoma:
Myeloma cells with B cells from Balb/c mice.

Absorption: 620-650nm

Emission: 660-670nm

Storage and Stability:
May be stored at 4C before opening. DO NOT FREEZE! Stable at 4C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.
TypeIsotypeCloneGrade
MabIgG2B11n186Affinity Purified
SizeStorageShippingSourceHost
100Tests4C Do Not FreezeBlue IceMouseRat
Concentration:
As reported
Immunogen:
Recombinant corresponding to mouse TSPAN8 expressed in CHO cells.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
Specificity:
Recognizes mouse TSPAN8.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.