Technical Data
T5010-11L
Thioredoxin Domain Containing 5 (Thioredoxin Domain-containing 5 (Endoplasmic Reticulum), TXNDC5, TXN5, Endothelial Protein Disulfide Isomerase, EndoPDI, ERP46, Hcc-2, MGC3178, PDIA15, Thioredoxin Like Protein p46, Thioredoxin-like Protein p46, UNQ364)
Description:
This is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C. Aliquots are stable for at least 3 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide: SLHRFVLSQAKDEL representing the C-terminus of the human protein (residues 347-360) according to NP_110437; NP_071368.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.
Specificity:
This antibody is expected to be able to recognize both reported human isoforms, as represented by NP_110437; NP_071368. Species Crossreactivity: Crossreacts with Human.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Sullivan DC et al. EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor. J Biol Chem 278:47079-88 (2003).