		Technical Data
T5010-11L	Thioredoxin Domain Containing 5 (Thioredoxin Domain-containing 5 (Endoplasmic Reticulum), TXNDC5, TXN5, Endothelial Protein Disulfide Isomerase, EndoPDI, ERP46, Hcc-2, MGC3178, PDIA15, Thioredoxin Like Protein p46, Thioredoxin-like Protein p46, UNQ364)

Description:
This is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide: SLHRFVLSQAKDEL representing the C-terminus of the human protein (residues 347-360) according to NP_110437; NP_071368.

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.

Specificity:

This antibody is expected to be able to recognize both reported human isoforms, as represented by NP_110437; NP_071368. Species Crossreactivity: Crossreacts with Human.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

Sullivan DC et al. EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor. J Biol Chem 278:47079-88 (2003).