Technical Data
T5010-11N
TXNDC5 (Thioredoxin Domain-containing Protein 5, Endoplasmic Reticulum Resident Protein 46, ER Protein 46, ERp46, Thioredoxin-like Protein p46, TLP46, UNQ364/PRO700)
Description:
This is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:64,000
Western Blot: 0.1-1ug/ml, observed in human placenta lysates on ~50kD bands
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-SLHRFVLSQAKDEL, from human TXNDC5, at C-terminal (NP_110437.2, NP_001139021.1).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:
Recognizes human TXNDC5.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Sullivan DC, Huminiecki L, Moore JW, Boyle JJ, Poulsom R, Creamer D, Barker J, Bicknell R. EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor. J Biol Chem. 2003 Nov 21;278(47):47079-88. Epub 2003 Sep 08.