Technical Data
T5010-11N1
TXNDC5 (Thioredoxin Domain-containing Protein 5, Endoplasmic Reticulum Resident Protein 46, ER Protein 46, ERp46, Thioredoxin-like Protein p46, TLP46, UNQ364/PRO700)
Description:
This is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:64,000
Western Blot: 0.03-0.1ug/ml, observed in human lymph nodes lysates on ~50+38kD bands
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-RDGKKVDQYKGKRD, from human TXNDC, at the internal region of the protein (NP_110437.2, NP_001139021.1).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:
Recognizes human TXNDC. Species sequence homology: Bovine and mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.