Technical Data
T5100-06N
THBS1, NT (Thrombospondin-1, TSP1, TSP)
Description:
THBS1 is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis,and tumorigenesis.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000
Immunohistochemistry: 1:10-1:50
Immunofluorescence: 1:10-1:50
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide corresponding to a portion of amino acids within aa181-210 from the N-terminal region of human THBS1 (P07996), conjugated to KLH. Species sequence homology: bovine
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human THBS1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Hofsteenge,J., et.al., J. Biol. Chem. 276(9), 6485-6498 (2001). 2. Roszmusz,E., et.al., Biochem. Biophys. Res. Commun. 296(1), 156-160 (2002).