Technical Data
T5101-09A
THSD1 (Thrombospondin Type-1 Domain-containing Protein 1, Transmembrane Molecule with Thrombospondin Module, Tmtsp) (PE)
Description:
THSD1 (thrombospondin type 1 domain-containing protein 1; also TMTSP) is a 90-100kD type I transmembrane protein that is reminiscent of Unc5h proteins. It is expressed on embryonic endothelial and hematopoietic stem cells and may be involved in cell-cell interactions. Mature human THSD1 is 827aa in length. It contains a 388aa extracellular domain (ECD; aa25-412) and a 418aa cytoplasmic region (aa434-851). The ECD possesses three Ig-like domains (aa156-316) and one TSP type-1 domain (aa340-393). There is one potential alternate start site at Met380 and two splice variants, one of which shows a deletion of aa341-393 and a second that shows a 36aa substitution for aa394-851, generating a soluble form. Over aa25-361, human THSD1 is 76% identical to mouse THSD1.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Hybridoma:
Myeloma with B cells from Balb/c mice.

Storage and Stability:
May be stored at 4C before opening. DO NOT FREEZE! Stable at 4C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
TypeIsotypeCloneGrade
MabIgG111C52Affinity Purified
SizeStorageShippingSourceHost
100Tests4C Do Not FreezeBlue IceHumanMouse
Concentration:
~0.02mg/ml
Immunogen:
NS0-derived, recombinant human THSD1 (rhTHSD1; aa25-361; Accession # Q9JM61).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in sodium chloride, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
Specificity:
Recognizes human THSD1. Species sequence homology: mouse (76%).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.