Technical Data
T5650
Titin (Connectin, TTN)
Description:
Connectin/titin is an ~ megadalton (MD) elastic filamentous protein of striated muscle sarcomeres. One connectin molecule spans from the Z line to the M line on the myosin filament in a half sarcomere, thus forming the third filament in addition to the myosin and actin filaments in a sarcomere. Connectin filaments position the myosin filaments at the center of a sarcomere as a spring and are responsible for passive tension generation when sarcomeres are stretched.

Applications:
Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry: 1:10
Western Blot: 1:10-1:20
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG12Q1063Supernatant
SizeStorageShippingSourceHost
1ml-20°CBlue IceHumanMouse
Concentration:
Not Determined
Immunogen:
Electrophoretically purified human skeletal muscle titin.
Purity:
Supernatant
Form
Supplied as a liquid, 0.1% sodium azide.
Specificity:
Recognizes human skeletal muscle titin. Species Crossreactivity: rabbit and mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.