		Technical Data
T8050	TLR1 (Toll Like Receptor 1, CD281)

Description:
Human toll-like receptor 1 (TLR-1) is a type 1 transmembrane protein that is expressed by peripheral blood leukocytes and other tissues such as spleen and thymus. TLR1 is thought to play a role in the innate immune response to microbial pathogens.

Applications:
Suitable for use in Flow Cytometry. Other applications have not been tested.

Recommended Dilution:
Flow Cytometry: 10ul labels 10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.

Hybridoma:
NS0/1 myeloma cells with spleen cells from Balb/c mice.

Recommended Negative Control:
I1904-78R: IgG1 Murine Negative Control

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Mab	IgG1	3F2	Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Mouse

Concentration:

0.5mg/ml

Immunogen:

TLR1 Fc fusion protein.

Purity:

Purified

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human toll-like receptor 1 (TLR-1). Does not cross react with TLR2, TLR4 or TLR4/MD-2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Whyllie, D. H. et al. (2000). Evidence for an accessory protein function for Toll-Like Receptor 1 in anti-bacterial responses. J. Immunol. 165: 7125–7132.