		Technical Data
T8050-01J	TLR1 (Toll Like Receptor 1, Toll-like Receptor 1 Precursor, CD281, CD281 Antigen, DKFZp547I0610, DKFZp564I0682, KIAA0012, MGC104956, MGC126311, MGC126312, rsc786, Similar to Drosophila Toll Protein, TIL, Toll (Drosophila) Homolog, Toll/Interleukin 1 Recep

Description:
CD281 is a type 1 transmembrane protein that is expressed by peripheral blood leukocytes and other tissues such as spleen and thymus.CD281, also known as toll-like receptor 1 (TLR-1), is thought to play a role in the innate immune response to microbial pathogens.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 1:10-1:100; 10ul labels 10e6 cells in 100ul
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Mab	IgG1	3F2	Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Mouse

Concentration:

~0.5mg/ml

Immunogen:

CD281 (TLR1) Fc fusion protein.

Purity:

Purified

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human CD281. Does not crossreact with CD282 (TLR2), CD284 (TLR4) or TLR4/MD-2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Whyllie, D. H. et al. (2000) Evidence for an accessory protein function for Toll-Like Receptor 1 in anti-bacterial responses. J. Immunol. 165: 7125 - 7132.