Technical Data
T8050-01J
TLR1 (Toll Like Receptor 1, Toll-like Receptor 1 Precursor, CD281, CD281 Antigen, DKFZp547I0610, DKFZp564I0682, KIAA0012, MGC104956, MGC126311, MGC126312, rsc786, Similar to Drosophila Toll Protein, TIL, Toll (Drosophila) Homolog, Toll/Interleukin 1 Recep
Description:
CD281 is a type 1 transmembrane protein that is expressed by peripheral blood leukocytes and other tissues such as spleen and thymus.CD281, also known as toll-like receptor 1 (TLR-1), is thought to play a role in the innate immune response to microbial pathogens.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 1:10-1:100; 10ul labels 10e6 cells in 100ul
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG13F2Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanMouse
Concentration:
~0.5mg/ml
Immunogen:
CD281 (TLR1) Fc fusion protein.
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human CD281. Does not crossreact with CD282 (TLR2), CD284 (TLR4) or TLR4/MD-2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Whyllie, D. H. et al. (2000) Evidence for an accessory protein function for Toll-Like Receptor 1 in anti-bacterial responses. J. Immunol. 165: 7125 - 7132.