		Technical Data
T8065-21B	Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha, TOP2, TOP2A, TP2A)

Description:
Topo II Beta antibody plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is present ubiquitously in normal cells and is upregulated in tumors and proliferating cells. Further, it is implicated in drug resistance of tumor cells.

Applications:
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
20ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.2mg/ml

Immunogen:

This antibody maps to a region between residue 1475 and 1525 of human DNA Topoisomerase II Beta using the numbering given in entry NP_001059.2 (GeneID 7155).

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide.

Specificity:

Species Crossreactivity: Human. Other species not tested.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.