Technical Data
TRAF5 (TNF Receptor Associated Factor 5, TNF Receptor-associated Factor 5, TRAF 5, TRAF-5, MGC-39780, RING Finger Protein 84, RNF84)
The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases. TRAFs are major signal transducers for both the TNF and IL-1:TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis. Recognizes TRAF5. Mouse TRAF5 is a 558aa protein.

Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
MabIgG55A219 Affinity Purified
50ug-20CBlue IceHumanMouse
As reported
Recombinant corresponding to aa77-186 of human TRAF5.
Purified by Protein G affinity chromatography.
Supplied as a liquid in PBS, 0.02% sodium azide.
Recognizes human TRAF5.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.