Technical Data
T8172-65C
TRAF6BP (TRAF6 Binding Protein, TRAF6-binding Protein, T6BP, CALCOCO3, PRO0105, Tax1 (Human T cell Leukemia Virus Type I) Binding Protein 1, Tax1 Binding Protein 1, Tax1 Binding Protein, TAX1BP1, TAX1BP1 Protein, TXBP151)
Description:
A TRAF-interacting protein that specifically associates with TRAF6. T6BP shares an overall 50% identity and 59% similarity to a recently identified chicken protein MDP62, which has been implicated in promoting neurite outgrowth. T6BP-TRAF6 complex formation is dependent on the presence of the IL-1 receptor-associated kinase (IRAK).

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 2-5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanRabbit
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to aa718-735 (CSEQFPPDYDQQVFERHV) of human Traf6BP.
Purity:
Purified by Protein G affinity Chromatography.
Form
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Specificity:
Recognizes human TRAF6BP/TAX1BP. Species sequence homology: 94% in mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Cao Z, et al. Nature 383: 443-446 (1996). 2. Darnay BG, et al. J Biol Chem 274 (12): 7724-7731 (1999). 3. Rothe M, et al. Cell 78: 681-692 (1994). 4. Cheng G, et al. Science 267: 1494-1498 (1995). 5. Nakane H, et al. J. Biol. Chem. 271: 14661-14664(1996). 6. Ling L. and Goeddel, DV. Proc. Natl. Acad. Sci.U.S.A. 97 (17), 9567-9572 (2000). 7. Uyeda, A., et al. Neurosci. Lett. 284: 61-64 (2000).