Technical Data
T8180
TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2L, TL2, TNFSF10)
10ug
50ug
Growth Factors, Cytokines Storage: -20CShipping: RT
Human TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2 Ligand), a 19.6kD protein consisting of 169 amino acid residues, is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells.

AA Sequence:
MRERGPQRVA AHITGTRGRS NTLSSPNSKN EKALGRKINS WESSRSGHSF LSNLHLRNGE LVIHEKGFYY IYSQTYFRFQ EEIKENTKND KQMVQYIYKY TSYPDPILLM KSARNSCWSK DAEYGLYSIY QGGIFELKEN DRIFVSVTNE HLIDMDHEAS FFGAFLVG

Storage and Stability:
Lyophilized powder may be stored at 4C for short-term only. Reconstitute to nominal volume by adding sterile dH2O, aliquot and store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
19.6kD
Source: E. coli

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Ehtesham, M., Cancer Research 62: 7170-7174 (2002). 2. Rokhlin, O.W., J. Biol. Chem. 277(36): 33,213-33,219 (2002). 3. Leaman, D.W., J. Biol. Chem. 277(32): 28,504-28,511 (2002). 4. Fulda, S., Nature Medicine 8: 808-815 (2002). 5. Chawla-Sarkar, M., J. of Immunology 169(2): 847-853 (2002). 6. Jeffrey, I.W., Cancer Research 62: 2272-2280 (2002). 7. Hao, C., Cancer Reserach 61: 1162-1170 (2001).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.