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Technical Data |
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T8180 |
TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2L, TL2, TNFSF10) |
10ug 50ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: RT |
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Human TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2 Ligand), a 19.6kD protein consisting of 169 amino acid residues, is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. AA Sequence: MRERGPQRVA AHITGTRGRS NTLSSPNSKN EKALGRKINS WESSRSGHSF LSNLHLRNGE LVIHEKGFYY IYSQTYFRFQ EEIKENTKND KQMVQYIYKY TSYPDPILLM KSARNSCWSK DAEYGLYSIY QGGIFELKEN DRIFVSVTNE HLIDMDHEAS FFGAFLVG Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile dH2O, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 19.6kD |
Source: E. coli Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Ehtesham, M., Cancer Research 62: 7170-7174 (2002). 2. Rokhlin, O.W., J. Biol. Chem. 277(36): 33,213-33,219 (2002). 3. Leaman, D.W., J. Biol. Chem. 277(32): 28,504-28,511 (2002). 4. Fulda, S., Nature Medicine 8: 808-815 (2002). 5. Chawla-Sarkar, M., J. of Immunology 169(2): 847-853 (2002). 6. Jeffrey, I.W., Cancer Research 62: 2272-2280 (2002). 7. Hao, C., Cancer Reserach 61: 1162-1170 (2001).
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