Technical Data
Transforming Growth Factor, beta-1, Recombinant, Human (TGFB1, CED, DPD1, TGFB, TGF-beta-1, Transforming Growth Factor beta 1, Camurati-Engelmann Disease)
Molecular Biology Storage: 4C Do not freezeShipping: Blue Ice
Human Transforming Growth Factor beta1 (TGF-beta1) is stimulatory for cells of mesenchymal origin and inhibitory for cells of epithelial or neuroectodermal origin. Mature TGF-beta1 is a disulfide-linked homodimer of two chains composed of 112aa residues each. There is a 70% homology between human TGF-beta1 and human TGF-beta2.

Biological Activity:
The biological activity of human TGF-beta1 is determined by measuring the acidification of the culture medium (Rat-1 cells) exposed to the growth factor.

Storage and Stability:
May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
Source: Bacteria
Purity: 98% pure by non-reduced SDS gel electrophoresis. Purified by sequential chromatography.
Concentration: ~0.2mg/ml
Form: Supplied as a liquid in 5mM HCl, pH 2.5.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Ichijo, H., et al., The Journal of Biological Chemistry 266(33): 22,459-22,464 (1994). 2. Yan, Z., et al., The Journal of Biological Chemistry 269(18): 13,231-13,237 (1994).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.