		Technical Data
T8264-46C	TMPRSS4 (Transmembrane Protease Serine 4, Channel-activating Protease 2, CAPH2, Membrane-type Serine Protease 2, MT-SP2, TMPRSS3, UNQ776/PRO1570)

Description:
This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1000
Western Blot: 1-3ug/ml, observed in human bone marrow lysates on ~48kD bands
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to DSTRCNADDAYQGE, from human TMPRSS4, at the internal region of the protein (NP_063947.1, NP_001077416.1).

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Specificity:

Recognizes human TMPRSS4. Species sequence homology: Mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Dawelbait G, Winter C, Zhang Y, Pilarsky C, Grutzmann R, Heinrich JC, Schroeder M. Structural templates predict novel protein interactions and targets from pancreas tumour gene expression data. Bioinformatics. 2007 Jul 1;23(13):i115-24.