		Technical Data
T8302-50A	TRF4-1 (Topoisomerase Related Function Protein 4 1, Topoisomerase-related Function Protein 4-1, TRF4 1, TRF41, TRF4, DNA Polymerase kappa, DNA Polymerase sigma, LAK1, LAK-1, PAP Associated Domain Containing 7, PAPD7, POLK, Polymerase (DNA-directed) sigma,

Description:
TRF4-1 is a nuclear protein whose expression is cell cycle-regulated at a post-transcriptional level. Two genes, TRF4-1 and TRF4-2, belonging to this family have been identified. TRF4 is also required to maintain a different aspect of higher order chromosome structure, sister chromatid cohesion.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
HeLa

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to aa447-462 of human TRF4-1.

Purity:

Purified by Protein G affinity Chromatography.

Form

Supplied as a liquid in PBS, 0.02% sodium azide.

Specificity:

Recognizes human TRF4-1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Walowsky C, Fitzhugh DJ, Castano IB, Ju JY, Levin NA, Christman MF. J Biol Chem 274 (11):7302-7308 (1999). 2. Castano IB, Brzoska PM, Sadoff BU, Chen H, Christman MF. Genes Dev 10 (20):2564-2576 (1996). 3. Castano IB, Heath-Pagliuso S, Sadoff BU, Fitzhugh DJ, Christman MF. Nucleic Acids Res 24(12): 2404-2410 (1996).