Technical Data
T8665-22
Troponin T, Cardiac (cTnT)
Description:
Troponin T, also known as TNNT2, is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with restrictive and dilated cardiomyopathy.

Applications:
Suitable for use in ELISA. Other applications have not been tested.

Recommended Dilutions:
ELISA: 1:500,000
Optimal dilutions to be determined by the researcher.

Matched Pair:
Capture: T8665-22
Detection: T8665-22D
Suitable for use as the detection or conjugate (label) antibody. Matched to T8665-22D as the capture or solid phase antibody.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG18.F.290Affinity Purified
SizeStorageShippingSourceHost
1mg-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Human Cardiac Troponin T
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
Specificity:
Recognizes human Cardiac Troponin T: 100%, human skeletal Troponin T: 0%.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. US Biological application reference: Oyamada, S. et al., (2011) J. Pharmacology and Exp. Therapeutics, doi: 10.1124/jpet.111.179697.