Technical Data
T9161-56Q
TRAF3, NT (TNF Receptor-associated Factor 3, CAP-1, CD40 Receptor-associated Factor 1, CRAF1, CD40-binding Protein, CD40BP, LMP1-associated Protein 1, LAP1, CAP1, CRAF1)
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Technical Data |
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T9161-56Q |
TRAF3, NT (TNF Receptor-associated Factor 3, CAP-1, CD40 Receptor-associated Factor 1, CRAF1, CD40-binding Protein, CD40BP, LMP1-associated Protein 1, LAP1, CAP1, CRAF1) |
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Description: MIP-T3 (microtubule-interacting protein associated with TRAF3) was originally identified in a yeast-two hybrid screen for proteins that interact with the tumor necrosis factor receptor (TNFR)-associated factor 3 (TRAF3). As a microtubule binding protein, MIP-T3 has been found to mediate the binding of DISC1 (disrupted-in-schizophrenia 1) to microtubules. MIP-T3 has also been shown to associate with IL13 receptor alpha (IL-13Ralpha1) and function as an inhibitor of IL-13 signaling. Recently, studies of the C. elegans homolog of MIP-T3 (DYF-11) have revealed that MIP-T3 is critical to cilium development; and in mammalian cells, MIP-T3 has been found to localize to basal bodies and cilia. Alternate names for MIP-T3 include TRAF3IP1, interleukin 13 receptor alpha1-binding protein 1, and TRAF3-interacting protein. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 2-4ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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