Technical Data
TRAF2 (TNF Receptor-associated Factor 2, E3 Ubiquitin-protein Ligase TRAF2, Tumor Necrosis Factor Type 2 Receptor-associated Protein 3, TRAP3)
TRAF2 is a 52kD protein which binds directly to TNF receptors and other TRAF proteins, transducing apoptotic and stress response signal cascades through adaptors including inhibitor of apoptosis proteins (IAPs). TRAF2 can also bind TNF receptors by forming a heterodimeric complex with TRAF1. Additionally TRAF2 forms a stronger, indirect, association with TNF receptors by forming a complex with apoptotic signal transducer (Tumor necrosis factor receptor associated death domain).

Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
MabIgG33A1293 Affinity Purified
50ug-20CBlue IceHumanMouse
Recombinant corresponding to aa205-222 of human TRAF2.
Purified by Protein G affinity chromatography.
Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
Recognizes human TRAF2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.