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Technical Data |
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T9162-73A |
Tumor Necrosis Factor Receptor 2, soluble (sTNFR-II), Recombinant, Human |
10ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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Recombinant sTNFR-II comprises a 184 amino acid fragment (23-206) corresponding to the mature sTNFR-II protein and is expressed in E. coli with an amino-terminal hexahistidine tag. Two types of soluble TNF receptors (sTNFR-I and sTNFR-II) have been identified, which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
Source: Human, Recombinant, E. coli Purity: Purified. 95% by SDS-PAGE. Concentration: As reported Form: Supplied as a liquid. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Wallach, D. et al., (1991) Agents Actions Suppl. 35: 51- 57.
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