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Technical Data |
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T9162-73C |
Tumor Necrosis Factor Receptor 2, Soluble, Recombinant, Human, Western Blot Control (Tumor Necrosis Factor Receptor Superfamily Member 1B, Tumor Necrosis Factor Receptor 2, TNF-R2, Tumor Necrosis Factor Receptor Type II, TNF-RII, TNFR-II, p75, p80 TNF-alp |
10ug |
| Growth Factors, Cytokines | Storage: -20°CShipping: Blue Ice |
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Two types of soluble TNF receptors (sTNFR-I and sTNFR-II) have been identified, which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women. Source: Recombinant corresponding to aa23-206 from mature human sTNFR-II, fused to 6x His-tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot as a control. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
Source: E. coli Purity: Purified (SDS-PAGE). Concentration: As reported Form: Supplied as a liquid in 25mM Tris-HCl, pH6.8, 50mM DTT, 1% SDS, 0.1% Bromophenol Blue, 2.5% glycerol. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Wallach, D. et al., (1991) Agents Actions Suppl. 35: 51- 57.
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