Technical Data
T9237-14A
Tyrosine Hydroxylase (TH, TYH, Tyrosine 3 Hydroxylase, Tyrosine 3 Monooxygenase)
Description:
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to dihydroxyphenylalanine (DOPA). It does so using tetrahydrobiopterin as a coenzyme. DOPA is a precursor for dopamine, which, in turn, is a precursor for norepinephrine (noradrenaline) and epinephrine (adrenaline). In humans, tyrosine hydroxylase is encoded by the TH gene.

Applications:
Suitable for use in Immunohistochemistry, Immunocytochemistry and Immunofluorescence. Other applications have not been tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG19.F.41Supernatant
SizeStorageShippingSourceHost
250ul-20CBlue IceMouse
Concentration:
Not Determined
Immunogen:
Purified tyrosine hydroxylase protein
Purity:
Supernatant
Form
Supplied as a liquid.
Specificity:
Recognizes Tyrosine Hydroxylase immunoreactive sites in the known catecholaminergic neurons and fiber systems of rat brain. It best recognizes the configuration of tyrosine hydroxylase in fixed tissues.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.