Technical Data
V2109-52A
Vascular Endothelial Cadherin (VE-Cadherin, CD144) (FITC)
Description:
Human vascular endothelium cadherin is an endothelium-specific cadherin localized at the intercellular junctions. The antibody can be used to investigate the functional role of VE-cadherin.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100Tests-20CBlue IceHumanRabbit
Concentration:
Not Determined
Immunogen:
Recombinant protein corresponding to aa1-258 of human VE-cadherin.
Purity:
Purified by immunoaffinity chromatography
Form
Supplied as a liquid in 50mM Tris, pH 7.3, 100mM sodium chloride, 1% BSA, 0.02% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:
Recognizes human VE-cadherin. Species Crossreactivity: mouse, rat and bovine
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Alteration of endothelial cell monolayer integrity triggers resynthesis of vascular endothelium cadherin: D. Gulino, et al.; J. Biol. Chem. 273, 29786 (1998) 2. VE-cadherin-p120 interaction is required for maintenance of endothelial barrier function: S. Iyer, et al.; Am. J. Physiol. Lung Cell Mol. Physiol. 286, L1143 (2004)