Technical Data
V2109-52A
Vascular Endothelial Cadherin (VE-Cadherin, CD144) (FITC)
Description:
Human vascular endothelium cadherin is an endothelium-specific cadherin localized at the intercellular junctions. The antibody can be used to investigate the functional role of VE-cadherin.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Note: Applications are based on unconjugated antibody.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100Tests-20CBlue IceHumanRabbit
Concentration:
Not Determined
Immunogen:
Recombinant protein corresponding to aa1-258 of human Vascular Endothelial Cadherin.
Purity:
Purified by immunoaffinity chromatography
Form
Supplied as a liquid in 50mM Tris, pH 7.3, 100mM sodium chloride, 1% BSA, 0.02% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:
Recognizes human Vascular Endothelial Cadherin. Species Crossreactivity: mouse, rat and bovine
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Alteration of endothelial cell monolayer integrity triggers resynthesis of vascular endothelium cadherin: D. Gulino, et al.; J. Biol. Chem. 273, 29786 (1998) 2. VE-cadherin-p120 interaction is required for maintenance of endothelial barrier function: S. Iyer, et al.; Am. J. Physiol. Lung Cell Mol. Physiol. 286, L1143 (2004)