		Technical Data
V2109-52A	Vascular Endothelial Cadherin (VE-Cadherin, CD144) (FITC)

Description:
Human vascular endothelium cadherin is an endothelium-specific cadherin localized at the intercellular junctions. The antibody can be used to investigate the functional role of VE-cadherin.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100 Tests		-20°C	Blue Ice	Human	Rabbit

Concentration:

Not Determined

Immunogen:

Recombinant protein corresponding to aa1-258 of human VE-cadherin.

Purity:

Purified by immunoaffinity chromatography

Form

Supplied as a liquid in 50mM Tris, pH 7.3, 100mM sodium chloride, 1% BSA, 0.02% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).

Specificity:

Recognizes human VE-cadherin. Species Crossreactivity: mouse, rat and bovine

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Alteration of endothelial cell monolayer integrity triggers resynthesis of vascular endothelium cadherin: D. Gulino, et al.; J. Biol. Chem. 273, 29786 (1998) 2. VE-cadherin-p120 interaction is required for maintenance of endothelial barrier function: S. Iyer, et al.; Am. J. Physiol. Lung Cell Mol. Physiol. 286, L1143 (2004)