Technical Data
V2110-15J
Vascular Endothelial Growth Factor 165, Recombinant, Human (VEGF 165)
2ug
10ug
Growth Factors, Cytokines Storage: -20CShipping: Blue Ice
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.

Biological Activity:
Fully biologically active when compared to standard. Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0ng/ml.

Endotoxin: 1EU/ug as determined by LAL method.

Storage and Stability:
Store lyophilized powder dessicated at 20C. Upon reconstitution, the preparation is stable for up to one week at 4C. For maximal stability, store the reconstituted preparation at -20C to -70C. Avoid repeated freeze/thaw cycles. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight:
38.2 kD
Source: Escherichia coli
Purity: ~95% by SDS-PAGE and HPLC analyses.
Concentration: 1mg/ml
Form: Supplied as a lyophilized powder in PBS, pH 7.5. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1mg/ml.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.