Technical Data
V2110-16D
Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1, FLT-1)
Description:
VEGFR-1 is a type I membrane protein. This protein binds VEGF, PLGF and VEGFB and belongs to the tyrosine protein kinase family. VEGFR-1 has a signaling role in mediating monocyte chemotaxis in tumor disease and performs an inhibitory role by sequestering VEGF and preventing its interaction with VEGFR-2.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilutions:
ELISA: 1:8000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG19F651Affinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Extracellular domain of human VEGFR-1 (106kD).
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2.
Specificity:
Recognizes extracellular domain of human VEGFR-1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Ferrara, N., et al., Nat. Med. 9: 669-676 (2003). 2. Cross, M.J., et al., Trends Biochem. Sci. 28: 488-494 (2003).