Technical Data
V2111-05A
Vascular Endothelial Statin (VE Statin, VE-Statin, Epidermal Growth Factor-like Domain Protein 7, EGF-like Domain 7, EGF-like Domain-containing Protein 7, EGF-like Domain Multiple 7, EGFL7, MGC111117, Multiple Epidermal Growth Factor-like Domain Protein 7
Description:
Vascular Endothelial Statin (EGLF7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:200-1:500
Immunohistochemistry: 1:100-1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG1,k9F489Ascites
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanMouse
Concentration:
Not determined.
Immunogen:
His-tagged EGFL-7 protein.
Purity:
Ascites
Form
Supplied as a lyophilized powder. No preservatives added. Reconstitute in 200ul sterile ddH2O.
Specificity:
Recognizes human Vascular Endothelial Statin at ~30kD.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.