Technical Data
V2115-26G
Vasoactive intestinal Polypeptide Receptor 2 (VIP Receptor 2, VIP2R, VIPR2, Helodermin Preferring VIP Receptor, Helodermin-preferring VIP Receptor, Pituitary Adenylate Cyclase Activating Polypeptide Type III Receptor, PACAP Type III Receptor, VPAC2, VPAC2
Description:
Vasoactive intestinal peptide receptor 2 (VPAC2) belongs to a family of three G protein-coupled receptors, which includes the related protein, VPAC1, and the pituitary adenylate cyclase-activating peptide receptor (PAC1). VPAC2 mediates the biological functions of the neuropeptide, vasoactive intestinal polypeptide (VIP), and, but with lower affinity, pituitary adenylate cyclase-activating peptide (PACAP), which are widely distributed throughout the brain and periphery.

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Western Blot: 1-10ug/ml
Immunohistochemistry (Frozen): 0.25-2ug/ml
Optimal dilutions to be determined by the researcher.

Control:
A431 Whole Cell Lysate

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG19F491Purified
SizeStorageShippingSourceHost
50ug-20°CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to aa105-122, FVDACGYSDPEDESKITF of human VIP Receptor 2. Cellular Localization: Integral membrane protein
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.08% sodium azide.
Specificity:
Recognizes human Vasoactive intestinal Polypeptide Receptor 2. at ~49kD. Species Crossreactivity: rat
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Lutz EM et al. Structure of the human VIPR2 gene for vasoactive intestinal peptide receptor type 2. FEBS Lett 458:197-203 (1999). Goetzl EJ et al. Specific recognition of the human neuroendocrine receptor for vasoactive intestinal peptide by anti-peptide antibodies. Mol Cell Neurosci 5:145-52 (1994).