Neurexins are heavily glycosylated and processed neuronal transmembrane cell surface proteins likely involved in cell recognition and adhesion. Antibody Anti-neurexin 3 alpha was made against a peptide immunogen corresponding to a stretch of aa’s in the extracellular domain of human neurexin 3 alpha. Although the theoretical full length of Neurexin 1alpha is 180kD, the protein detected in human brain lysates may show a band around 180kD and additional bands around 40-55kD as a possible result of the posttranslational processing previously reported.

Suitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.

Immunohistochemistry: Requires antigen retrieval using heat treatment prior to staining paraffin sections. Sodium citrate buffer, pH 6.0 is recommended. Optimal dilutions to be determined by the researcher.

PC12 cell lysate

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

KLH-conjugated linear peptide corresponding to a stretch of amino acids in the extracellular domain of human Neurexin 3

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.

Purified by affinity chromatography

Recognizes human Neurexin3. Species Crossreactivity: mouse and rat