Technical Data

030440
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG2a
Clone Number
13B518
Grade
Purified
Applications
E
Crossreactivity
Hu
Gene ID
9833
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-MELK
HPK38

Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.

Applications
ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthesized peptide of human MELK(AA: 637-651:C-VYKRLVEDILSSCKV).
Form
Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer.
Purity
Purified
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Neuro Oncol. 2011 Jun;13(6):622-34. |2. Breast Cancer Res. 2009;11(4):R60.|
USBio References
No references available
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