Technical Data

030620
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1
Clone Number
13B698
Grade
Ascites
Applications
E WB
Crossreactivity
Hu Mk Mo
Gene ID
9869
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-SETDB1
ESET; KG1T; KMT1E; KIAA0067; H3-K9-HMTase4; SETDB1

This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression.Tissue specificity: Widely expressed. High expression in testis.

Applications
Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Purified recombinant fragment of human SETDB1 expressed in E. coli.
Form
Supplied as a liquid, 0.03% sodium azide.
Purity
Ascites
Specificity
Human, Mouse, Monkey

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Proteomics. 2005 Sep;5(14):3589-99.|2. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5308-13.|3. Mol Cell Biochem. 2007 Nov;305(1-2):35-44.
USBio References
No references available
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