Technical Data

030699
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1
Clone Number
13B777
Grade
Purified
Applications
E FC WB
Crossreactivity
Hu
Gene ID
7205
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-TRIP6 (Thyroid Receptor-interacting Protein 6, TR-interacting Protein 6, TRIP-6, Opa-interacting Protein 1, OIP-1, Zyxin-related Protein 1, ZRP-1, OIP1)

This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Applications
Western Blot: 1:500-1:2000 Flow Cytometry: 1:200-1:400 ELISA: 1:10000 proposed
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Purified recombinant fragment of human TRIP6 (AA: 107-291) expressed in E. coli.
Form
Supplied as a liquid in PBS, 0.05% sodium azide
Purity
Purified
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1.Biol Cell. 2011 Dec 1;103(12):573-91. 2.Mol Cell Biol. 2010 Dec;30(23):5582-96.
USBio References
No references available
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