Technical Data

030825
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgM
Clone Number
406CT21.4.3
Grade
Ascites
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001029124.1; NP_001732.1
Gene ID
796
Gene #
CALCA
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-CALCA/CT (CALCA, CALC1, Calcitonin, Katacalcin, Calcitonin carboxyl-terminal peptide, PDN-21)
CALCA, CALC1, Calcitonin, Katacalcin, Calcitonin carboxyl-terminal peptide, PDN-21

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications
Suitable for use in Western Blot, ELISA.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:1000~8000
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Purified His-tagged CALCA/CT protein (fragment).
Form
Supplied as a liquid, 0.09% sodium azide.
Purity
Ascites
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Giroux, S., et al. Bone 47(5):975-981(2010)|Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Lee, J.Y., et al. Korean J Lab Med 30(4):406-413(2010)|Giovanella, L., et al. Clin. Chem. Lab. Med. 48(8):1163-1165(2010)|Hatzistilianou, M. ScientificWorldJournal 10, 1941-1946 (2010)
USBio References
No references available
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