Technical Data

031137
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1
Clone Number
407CT20.1.2
Grade
Ascites
Applications
E WB
Crossreactivity
Hu
Accession #
NP_068769.2; NP_690605.1
Gene ID
931
Gene #
MS4A1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-MS4A1, CD20, CT (MS4A1, CD20, B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD_antigen=CD20)
MS4A1, CD20, B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD_antigen=CD20

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.

Applications
Suitable for use in Western Blot, ELISA.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:1000~3200
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MS4A1/CD20 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the C-term region of human MS4A1/CD20.
Form
Supplied as a liquid, 0.09% sodium azide.
Purity
Ascites
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Weber, M.S., et al. Ann. Neurol. 68(3):369-383(2010)|Wu, D., et al. Am. J. Clin. Pathol. 134(2):258-265(2010)|de Haij, S., et al. Cancer Res. 70(8):3209-3217(2010)|Beers, S.A., et al. Semin. Hematol. 47(2):107-114(2010)|Davila, S., et al. Genes Immun. 11(3):232-238(2010)
USBio References
No references available
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