Technical Data

031199
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1
Clone Number
632CT5.11.4
Grade
Ascites
Applications
E WB
Crossreactivity
Hu
Accession #
NP_005388.2
Gene ID
5420
Gene #
PODXL
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-Podocalyxin, CT (Podocalyxin-like protein-1, PC, PCLP, PCLP1, PODXL, MGC138240, GCTM-2 Antigen Gp200)

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Applications
Suitable for use in Western Blot, ELISA.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:500~16000
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PODXL Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human PODXL.
Form
Supplied as a liquid, 0.09% sodium azide.
Purity
Ascites
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Schopperle, W.M., et al. Biochem. Biophys. Res. Commun. 398(3):372-376(2010)|Hsu, Y.H., et al. Am. J. Pathol. 176(6):3050-3061(2010)|Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)|Drossopoulou, G.I., et al. Am. J. Physiol. Renal Physiol. 297 (3), F594-F603 (2009)|Thomas, S.N., et al. Am. J. Physiol., Cell Physiol. 296 (3), C505-C513 (2009)
USBio References
No references available
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