Technical Data

031320
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1,k
Clone Number
346CT2.2.1
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_004172.2;
Gene ID
7345
Gene #
UCHL1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mouse Anti-UCHL1 (UCHL1, Ubiquitin carboxyl-terminal hydrolase isozyme L1, Neuron cytoplasmic protein 9.5, PGP 9.5, Ubiquitin thioesterase L1)
UCHL1, Ubiquitin carboxyl-terminal hydrolase isozyme L1, Neuron cytoplasmic protein 9.5, PGP 9.5, Ubiquitin thioesterase L1

The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

Applications
Suitable for use in Western Blot, ELISA.
Recommended Dilution
ELISA: 1:1000 Western Blot: 1:120~1000
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
UCHL1 Mab is generated from mouse immunized with UCHL1 recombinant protein.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein G affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Martins-de-Souza, D., et al. J Psychiatr Res 44(14):989-991(2010)|Hussain, S., et al. Leukemia 24(9):1641-1655(2010)|Ma, Y., et al. J. Cell. Biochem. 110(6):1512-1519(2010)|Wu, Y.R., et al. Clin. Chim. Acta 411 (13-14), 955-958 (2010)|Li, L., et al. Clin. Cancer Res. 16(11):2949-2958(2010)
USBio References
No references available
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