Technical Data

031476
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Mo
Accession #
NP_150229.2
Gene ID
94160
Gene #
ABCC12
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ABCC12, ID (ABCC12, MRP9, Multidrug resistance-associated protein 9, ATP-binding cassette sub-family C member 12)
ABCC12, MRP9, Multidrug resistance-associated protein 9, ATP-binding cassette sub-family C member 12

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-751 amino acids from the Central region of human ABCC12.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Haimeur, A., et al. Curr. Drug Metab. 5(1):21-53(2004)|Bera, T.K., et al. Proc. Natl. Acad. Sci. U.S.A. 99(10):6997-7002(2002)|Yabuuchi, H., et al. Biochem. Biophys. Res. Commun. 288(4):933-939(2001)|Tammur, J., et al. Gene 273(1):89-96(2001)
USBio References
No references available
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