Technical Data

031479
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_005682.2; O60706
Gene ID
10060
Gene #
ABCC9
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ABCC9, ID (ABCC9, SUR2, ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2)
ABCC9, SUR2, ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ABCC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-669 amino acids from the Central region of human ABCC9.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)|Ellis, J.A., et al. Physiol. Genomics 40(3):184-188(2010)|Kim, S.J., et al. Biochem. Biophys. Res. Commun. 391(1):974-978(2010)|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
USBio References
No references available
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