Technical Data

031508-PE
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Conjugate
PE
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA WB
Crossreactivity
Hu
Accession #
NP_001082.2
Gene ID
26
Gene #
ABP1
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
Preservative Free
Rabbit Anti-ABP1, NT (ABP1, AOC1, DAO1, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein, Histaminase, Kidney amine oxidase) (PE)
ABP1, AOC1, DAO1, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein, Histaminase, Kidney amine oxidase

This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

Applications
Suitable for use in Western Blot and FLISA. Other applications not tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 71-100 in the N-terminal region of human ABP1.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ABP1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) 2. McGrath, A.P., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 2), 137-142 (2010) 3. Chambers, J.C., et al. Nat. Genet. 42(2):149-152(2010) 4. McGrath, A.P., et al. Biochemistry 48(41):9810-9822(2009) 5. Song, W.B., et al. World J. Gastroenterol. 15(31):3916-3919(2009)
USBio References
No references available
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